PEPTIDES·INDEX
72 peptides417 listingsUpdated 6h agoBuild My Stack
Library

SLU-PP-915Metabolic / Exercise Mimetics

Orally active ERR agonist studied in mice as an exercise mimetic; a small molecule, not a peptide.

Rating1/5SpeculativeHuman dataSafety
Compare prices — from $76.50
StatusResearch only
FDA-approvedNO
PrescriptionNO
From$76.50

Overview

SLU-PP-915 is a synthetic small molecule — not a peptide (a thiophene boronic-acid compound) developed by the Saint Louis University / Burris group as an orally active successor to SLU-PP-332. Like its predecessor it is a pan-agonist of the estrogen-related receptors (ERRalpha/beta/gamma), and it has been researched as an "exercise mimetic" and for heart failure in mice only, where it increased running endurance and improved cardiac function. It has never been tested in humans. It is not FDA-evaluated and is sold for laboratory research only; nothing here is medical or dosing advice.

Related compounds

SLU-PP-332 TabletsMetabolic / Exercise MimeticsERR agonist studied for metabolism and endurance.O-304Metabolic / Exercise MimeticsPan-AMPK activator studied for blood sugar and exercise capacity; a small molecule, not a peptide.

Sources

Starting references for the library summary. These are not dosing instructions or medical advice.

Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915European Journal of Medicinal Chemistrypubmed.ncbi.nlm.nih.gov/37421886/…Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial FunctionCirculationpubmed.ncbi.nlm.nih.gov/37961903/…An orally active estrogen receptor-related receptor agonist, SLU-PP-915, enhances aerobic exercise capacityJournal of Pharmacology and Experimental Therapeuticspubmed.ncbi.nlm.nih.gov/41421047/…

For research-use educational context only. Not medical advice and not a recommendation to use any compound. Consult a qualified healthcare professional before any health decision.